Diffuse Melanosis and Ascites due to Metastatic Malignant Melanoma

Diffuse Cutaneous Melanosis Associated with Malignant Melanoma.

780 Ann Dermatol Received December 10, 2014, Revised February 7, 2015, Accepted for publication February 18, 2015 Corresponding author: Joanna Mangana, Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, CH 8091, Zurich, Switzerland. Tel: 41-44-255-3155, Fax: 41-44-255-454, E-mail: johanna. mangana@ usz.ch This is an Open Access article distributed under the terms of the Cr...

Diffuse cutaneous melanosis: rare complication of metastatic melanoma*

Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression...

Fulminant hepatic failure due to metastatic choroidal melanoma

Diffuse melanosis cutis related to dermal micrometastases as the first clinical symptom of distant metastatic malignant melanoma

RATIONALE Diffuse melanosis cutis (DMC) is a very rare sign of malignant melanoma progression. The condition usually develops after approximately one year from melanoma diagnosis in a patient with metastatic tumors and after anticancer treatment with cytostatic medications. PATIENT CONCERNS A 72-year old Caucasian man was admitted to the Department of Dermatology with DMC for 4 months and the...

Neurocutaneous Melanosis with Malignant Leptomeningeal Melanoma

Neurocutaneous melanosis (NCM) is a rare congenital syndrome characterized by the presence of large or multiple congenital melanocytic nevi with either benign or malignant pigmented cell tumors of the leptomeninges. We report a case of NCM in a patient with previously robust health. No neurological deficit was noted in the patient. At the age of 21 years old, blurred vision initially appeared. ...